128 research outputs found
HI Observations of the Supermassive Binary Black Hole System in 0402+379
We have recently discovered a supermassive binary black hole system with a
projected separation between the two black holes of 7.3 parsecs in the radio
galaxy 0402+379. This is the most compact supermassive binary black hole pair
yet imaged by more than two orders of magnitude. We present Global VLBI
observations at 1.3464 GHz of this radio galaxy, taken to improve the quality
of the HI data. Two absorption lines are found toward the southern jet of the
source, one redshifted by 370 +/- 10 km/s and the other blueshifted by 700 +/-
10 km/s with respect to the systemic velocity of the source, which, along with
the results obtained for the opacity distribution over the source, suggests the
presence of two mass clumps rotating around the central region of the source.
We propose a model consisting of a geometrically thick disk, of which we only
see a couple of clumps, that reproduces the velocities measured from the HI
absorption profiles. These clumps rotate in circular Keplerian orbits around an
axis that crosses one of the supermassive black holes of the binary system in
0402+379. We find an upper limit for the inclination angle of the twin jets of
the source to the line of sight of 66 degrees, which, according to the proposed
model, implies a lower limit on the central mass of ~7 x 10^8 Msun and a lower
limit for the scale height of the thick disk of ~12 pc .Comment: 20 pages, 7 figures. Accepted on the Astrophysical Journa
Bacterial isolates from patients with preterm labor with and without preterm rupture of the fetal membranes.
OBJECTIVE: The aim of this study is to describe the bacterial flora of women in preterm labor with or without premature rupture of membranes. METHODS: Retrospective studies of 239 patients with preterm labor were performed. RESULTS: One hundred and twenty-three of 239 patients with preterm labor (51.5%) had bacterial vaginosis. Seventy of the 239 patients with preterm labor (29.3%) developed premature rupture of the membranes (preterm PROM). Of the 70 patients with preterm PROM, 51 (72.9%) had bacterial vaginosis. Therefore, 51 of the 123 patients with bacterial vaginosis (41.5%) developed preterm PROM. An increased number of organisms detected from the vaginal discharge in patients with preterm labor was associated with preterm PROM by Cochran-Armitage test. An increased number of organisms detected from the vaginal discharge in patients with preterm labor complicated with bacterial vaginosis was significantly associated with preterm PROM by Cochran-Armitage test. CONCLUSIONS: In preterm labor, the number of different species detected in the vagina provide sensitive and specific prediction of preterm PROM in patients with preterm labor
Feature issue of digital holography and 3D imaging (DH) introduction
The OSA Topical Meeting "Digital Holography and 3D Imaging (DH)," was held in Seattle, Washington, July 13-17, 2014. Feature issues based on the DH meeting series have been released by Applied Optics (AO) since 2007. This year Optics Express (OE) and AO jointly decided to have one such feature issue in each journal. The DH meeting will continue in the future, as expected, and the next meeting is scheduled to be held on 24-28 May 2015, in Shanghai Institute of Optics and Fine Mechanics, Shanghai, China. © 2014 Optical Society of Americ
Proposed method for searches of gravitational waves from PKS 2155-304 and other blazar flares
We propose to search for gravitational waves from PKS 2155-304 as well as
other blazars. PKS 2155-304 emitted a long duration energetic flare in July
2006, with total isotropic equivalent energy released in TeV gamma rays of
approximately ergs. Any possible gravitational wave signals
associated with this outburst should be seen by gravitational wave detectors at
the same time as the electromagnetic signal. During this flare, the two LIGO
interferometers at Hanford and the GEO detector were in operation and
collecting data. For this search we will use the data from multiple
gravitational wave detectors. The method we use for this purpose is a coherent
network analysis algorithm and is called {\tt RIDGE}. To estimate the
sensitivity of the search, we perform numerical simulations. The sensitivity to
estimated gravitational wave energy at the source is about
ergs for a detection probability of 20%. For this search, an end-to-end
analysis pipeline has been developed, which takes into account the motion of
the source across the sky.Comment: 10 pages, 7 figures. Contribution to 12th Gravitational Wave Data
Analysis Workshop. Submitted to Classical and Quantum Gravity. Changes in
response to referee comment
Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis
Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments. In vivo monocyte progenitors populate all tissues for immune surveillance which supports the maintenance of homeostasis as well as regaining homeostasis after injury. Here we propose to classify macrophage phenotypes according to prototypical tissue environments, e.g. as they occur during homeostasis as well as during the different phases of (dermal) wound healing. In tissue necrosis and/or infection, damage- and/or pathogen-associated molecular patterns induce proinflammatory macrophages by Toll-like receptors or inflammasomes. Such classically activated macrophages contribute to further tissue inflammation and damage. Apoptotic cells and antiinflammatory cytokines dominate in postinflammatory tissues which induce macrophages to produce more antiinflammatory mediators. Similarly, tumor-associated macrophages also confer immunosuppression in tumor stroma. Insufficient parenchymal healing despite abundant growth factors pushes macrophages to gain a profibrotic phenotype and promote fibrocyte recruitment which both enforce tissue scarring. Ischemic scars are largely devoid of cytokines and growth factors so that fibrolytic macrophages that predominantly secrete proteases digest the excess extracellular matrix. Together, macrophages stabilize their surrounding tissue microenvironments by adapting different phenotypes as feed-forward mechanisms to maintain tissue homeostasis or regain it following injury. Furthermore, macrophage heterogeneity in healthy or injured tissues mirrors spatial and temporal differences in microenvironments during the various stages of tissue injury and repair. Copyright (C) 2012 S. Karger AG, Base
Establishing accretion flares from massive black holes as a major source of high-energy neutrinos
High-energy neutrinos have thus far been observed in coincidence with
time-variable emission from three different accreting black holes: a gamma-ray
flare from a blazar (TXS 0506+056), an optical transient following a stellar
tidal disruption (AT2019dsg), and an optical outburst from an active galactic
nucleus (AT2019fdr). Here we present a unified explanation for the latter two
of these sources: accretion flares that reach the Eddington limit. A signature
of these events is a luminous infrared reverberation signal from circumnuclear
dust that is heated by the flare. Using this property we construct a sample of
similar sources, revealing a third event coincident with a PeV-scale neutrino.
This sample of three accretion flares is correlated with high-energy neutrinos
at a significance of 3.7 sigma. Super-Eddington accretion could explain the
high particle acceleration efficiency of this new population.Comment: 46 pages, 11 figures, 3 table
Menus for Feeding Black Holes
Black holes are the ultimate prisons of the Universe, regions of spacetime
where the enormous gravity prohibits matter or even light to escape to
infinity. Yet, matter falling toward the black holes may shine spectacularly,
generating the strongest source of radiation. These sources provide us with
astrophysical laboratories of extreme physical conditions that cannot be
realized on Earth. This chapter offers a review of the basic menus for feeding
matter onto black holes and discusses their observational implications.Comment: 27 pages. Accepted for publication in Space Science Reviews. Also to
appear in hard cover in the Space Sciences Series of ISSI "The Physics of
Accretion onto Black Holes" (Springer Publisher
Supermassive Black Hole Binaries: The Search Continues
Gravitationally bound supermassive black hole binaries (SBHBs) are thought to
be a natural product of galactic mergers and growth of the large scale
structure in the universe. They however remain observationally elusive, thus
raising a question about characteristic observational signatures associated
with these systems. In this conference proceeding I discuss current theoretical
understanding and latest advances and prospects in observational searches for
SBHBs.Comment: 17 pages, 4 figures. To appear in the Proceedings of 2014 Sant Cugat
Forum on Astrophysics. Astrophysics and Space Science Proceedings, ed.
C.Sopuerta (Berlin: Springer-Verlag
Photo-designed terahertz devices
Technologies are being developed to manipulate electromagnetic waves using artificially structured materials such as photonic crystals and metamaterials, with the goal of creating primary optical devices. For example, artificial metallic periodic structures show potential for the construction of devices operating in the terahertz frequency regime. Here we demonstrate the fabrication of photo-designed terahertz devices that enable the real-time, wide-range frequency modulation of terahertz electromagnetic waves. These devices are comprised of a photo-induced, planar periodic-conductive structure formed by the irradiation of a silicon surface using a spatially modulated, femtosecond optical pulsed laser. We also show that the modulation frequency can be tuned by the structural periodicity, but is hardly affected by the excitation power of the optical pump pulse. We expect that our findings will pave the way for the construction of all-optical compact operating devices, such as optical integrated circuits, thereby eliminating the need for materials fabrication processes
Elliptical Galaxies and Bulges of Disk Galaxies: Summary of Progress and Outstanding Issues
This is the summary chapter of a review book on galaxy bulges. Bulge
properties and formation histories are more varied than those of ellipticals. I
emphasize two advances: 1 - "Classical bulges" are observationally
indistinguishable from ellipticals, and like them, are thought to form by major
galaxy mergers. "Disky pseudobulges" are diskier and more actively star-forming
(except in S0s) than are ellipticals. Theys are products of the slow
("secular") evolution of galaxy disks: bars and other nonaxisymmetries move
disk gas toward the center, where it starbursts and builds relatively flat,
rapidly rotating components. This secular evolution is a new area of galaxy
evolution work that complements hierarchical clustering. 2 - Disks of
high-redshift galaxies are unstable to the formation of mass clumps that sink
to the center and merge - an alternative channel for the formation of classical
bulges. I review successes and unsolved problems in the formation of
bulges+ellipticals and their coevolution (or not) with supermassive black
holes. I present an observer's perspective on simulations of dark matter galaxy
formation including baryons. I review how our picture of the quenching of star
formation is becoming general and secure at redshifts z < 1. The biggest
challenge is to produce realistic bulges+ellipticals and disks that overlap
over a factor of 10**3 in mass but that differ from each other as observed over
that whole range. Second, how does hierarchical clustering make so many giant,
bulgeless galaxies in field but not cluster environments? I argue that we rely
too much on AGN and star-formation feedback to solve these challenges.Comment: 46 pages, 10 postscript figures, accepted for publication in Galactic
Bulges, ed. E. Laurikainen, R. F. Peletier, & D. A. Gadotti (New York:
Springer), in press (2015
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